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Recent advances in neuroimaging technology allowing for in vivo quantification of GSH levels in the brain have shown decreased GSH in patients with MS compared to healthy controls, with the degree of depletion correlating with disease severity and showing parallel longitudinal decline over time ( 5 Future directions The clinical load of neurodegenerative diseases like AD and PD is projected to increase exponentially in coming years, with a commensurate increase in need for potential treatments

dosages greater than 12 g per day may cause minor gastrointestinal intolerance (e.g., nausea, diarrhea) [42]

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